Research Article
[Retracted] Leukemia Inhibitory Factor Facilitates Self-Renewal and Differentiation and Attenuates Oxidative Stress of BMSCs by Activating PI3K/AKT Signaling
Figure 11
Implantation of LIF-overexpressed BMSC-loaded BCP scaffolds alleviates oxidative stress through PI3K/Akt signaling. (a–j) Immunohistochemical staining for LIF, LIFR, gp130, PI3K, p-PI3K, AKT, p-AKT, Nrf2, and GPx-3 expressions in the murine calvarial bone defect with LIF-overexpressed, PI3K/Akt signaling agonist 740Y-P or inhibitor LY294002 BMSC-loaded BCP scaffolds. Bar, 20 μm.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |
(i) |
(j) |