Transcriptomics Coupled to Proteomics Reveals Novel Targets for the Protective Role of Spermine in Diabetic Cardiomyopathy

Figure 3

Transcriptome profiles for the myocardium of CK, DbCM, and SPM mice. (a) The heat map showing the 174 overlapped genes producing differentially expressed in DbCM and reversed expression by SPM. Red color shows the genes with significantly elevated transcription levels, and green color shows the genes with significantly reduced transcription levels. (b) KEGG pathway analysis of the DEGs belonging to metabolic related pathways of DbCM/CK. (c) KEGG pathway analysis of the DEGs belonging to metabolic related pathways of SPM/DbCM. Numbers and values of DEGs in each pathway.

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