Transcriptomics Coupled to Proteomics Reveals Novel Targets for the Protective Role of Spermine in Diabetic Cardiomyopathy

Figure 6

Identification of proteome changes in DbCM. (a) The amounts of differentially expressed proteins by comparing DbCM to CK. (b) KEGG pathway analysis of the DEPs belonging to metabolic related pathways of DbCM/CK. Numbers and values of DEPs in each pathway. (c) Venn diagrams showing the 37 overlapped candidates that differentially expressed on both RNA level and protein level. (d) Protein-protein interaction network analysis on metabolic pathway-related candidates between DbCM and CK.

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