Research Article

EID3 Promotes Cancer Stem Cell-Like Phenotypes in Osteosarcoma through the Activation of PI3K-AKT Signaling Pathway

Figure 3

EID3 overexpression promotes stemness of MG-63 cells. (a) Cytometry analysis of CD133+ cells in MG-63-EID3 and MG-63-Vector cells. (b) Overexpression of EID3 upregulated mRNA levels of osteosarcoma stem cell markers OCT3/4, ABCG2, and NANOG. (c) Overexpression of EID3 upregulated protein levels of osteosarcoma stem cell markers OCT3/4, ABCG2, and NANOG. (d) Western blot analysis of protein levels of stem cell marker SOX2. All data are presented as (). , ; , ; , .
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