Research Article

Pursuing Diabetic Nephropathy through Aqueous Humor Proteomics Analysis

Table 2

Significantly differentially expressed proteins.

Descriptionp.t. testFold-changeExpress

A0A0A0MT36Immunoglobulin kappa variable 6D-21 (nonfunctional)(IGKV6D-21)0.0369552233.57463889Upregulate
A0A0C4DH25Immunoglobulin kappa variable 3D-20 (IGKV3D-20)0.0494936812.128066835Upregulate
A0A286YEY1Immunoglobulin heavy constant alpha 1 (IGHA1)0.0289491072.110253625Upregulate
B4E1Z4Complement factor B (ENSP00000410815)0.0264563771.992205397Upregulate
E7ES19Thrombospondin 4 (THBS4)0.0173079642.481397525Upregulate
P00742Coagulation factor X (F10)0.0378253621.773541552Upregulate
P00747Plasminogen (PLG)0.0362833961.661644313Upregulate
P01008Serpin family C member 1 (SERPINC1)0.0301046271.601734876Upregulate
P01024Complement C3 (C3)0.044651751.521368772Upregulate
P01602Immunoglobulin kappa variable 1-5 (IGKV1-5)0.0251827412.001283426Upregulate
P01709Immunoglobulin lambda variable 2-8 (IGLV2-8)0.0402651651.711371053Upregulate
P02749Apolipoprotein H (APOH)0.0393176192.55723495Upregulate
P02753Retinol binding protein 4 (RBP4)0.0386949821.88456551Upregulate
P07357Complement C8 alpha chain (C8A)0.0372868561.950270583Upregulate
P22314Ubiquitin like modifier activating enzyme 1 (UBA1)0.0364263843.419798742Upregulate
P25311Alpha-2-glycoprotein 1, zinc-binding (AZGP1)0.0062820182.078922885Upregulate
P80188Lipocalin 2 (LCN2)0.0206890342.250249072Upregulate
Q15828Cystatin E/M (CST6)0.0158884213.585016053Upregulate
Q5T123SH3 domain binding glutamate rich protein like 3 (SH3BGRL3)0.0050802052.546679302Upregulate
A0A087WX77Neural cell adhesion molecule 1 (NCAM1)0.0135200810.362177114Downregulate
A0A087X0M8Cell adhesion molecule L1 like (CHL1)0.0023969420.447154673Downregulate
A0A087X0S5Collagen type VI alpha 1 chain (COL6A1)0.0023273370.556691701Downregulate
A0A087X1J7Glutathione peroxidase 3 (GPX3)0.0426045950.636518049Downregulate
A0A2R8Y7U1Tripeptidyl peptidase 1 (TPP1)0.0072848980.324649629Downregulate
C9IZG4cutA divalent cation tolerance homolog (CUTA)0.0148647470.323983214Downregulate
C9JIZ6Prosaposin (PSAP)0.0446219130.51799473Downregulate
C9JYY6Neuronal cell adhesion molecule (NRCAM)0.0115082260.450951245Downregulate
E9PF17Versican (VCAN)0.0383600040.257367031Downregulate
F6S8M0Glucosamine (N-acetyl)-6-sulfatase (GNS)0.0122243580.341371268Downregulate
F6VDH7ST13 Hsp70 interacting protein (ST13)0.0198270160.200673989Downregulate
H0YF95Seizure related 6 homolog (SEZ6)0.0133504890.371791006Downregulate
K7ELL7Protein kinase C substrate 80 K-H (PRKCSH)0.0176354370.43953481Downregulate
O43505Beta-1,4-glucuronyltransferase 1 (B4GAT1)0.0459004290.662871362Downregulate
O60575Serine peptidase inhibitor Kazal type 4 (SPINK4)0.0462741310.436778293Downregulate
O75882Attractin (ATRN)0.0329121430.603382567Downregulate
O95445Apolipoprotein M (APOM)0.0111955210.27929918Downregulate
P10745Retinol binding protein 3 (RBP3)0.0002565350.294947516Downregulate
P12110Collagen type VI alpha 2 chain (COL6A2)0.0412365140.371699968Downregulate
P15291Beta-1,4-galactosyltransferase 1 (B4GALT1)0.034775540.458653103Downregulate
P19022Cadherin 2 (CDH2)0.0292169730.468621717Downregulate
P20849Collagen type IX alpha 1 chain (COL9A1)0.006699320.287809307Downregulate
P23471Protein tyrosine phosphatase receptor type Z1 (PTPRZ1)0.0055343320.378623205Downregulate
P43251Biotinidase (BTD)0.0184180730.582873713Downregulate
Q02818Nucleobindin 1 (NUCB1)0.0350504980.482356964Downregulate
Q14563Semaphorin 3A (SEMA3A)0.0177460650.317266926Downregulate
Q15223NECTIN cell adhesion molecule 1 (NECTIN1)0.0011704440.188635993Downregulate
Q15904ATPase H+ transporting accessory protein 1 (ATP6AP1)0.0036941910.314344708Downregulate
Q6UX71Plexin domain containing 2 (PLXDC2)0.0318132230.559106065Downregulate
Q8WXD2Secretogranin III (SCG3)0.0142930570.455315443Downregulate
Q96JP9Cadherin related family member 1 (CDHR1)0.0141559710.262671062Downregulate
Q99784Olfactomedin 1 (OLFM1)0.0132022710.386150368Downregulate
Q9BRK5Stromal cell derived factor 4 (SDF4)0.0097526380.243429438Downregulate
Q9BTY2Alpha-L-fucosidase 2 (FUCA2)0.0382173130.576768404Downregulate
Q9HAT2Sialic acid acetylesterase (SIAE)0.0201620570.466031421Downregulate