Pursuing Diabetic Nephropathy through Aqueous Humor Proteomics Analysis

Table 4

Functional enrichment involving renal and urological disease for differentially expressed proteins.

Categories	Functions	Diseases or functions annotation	value	Molecules	# molecules
Cardiovascular disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease	Renal vein thrombosis	Renal vein thrombosis	0.0000364	F10, SERPINC1	2
Cellular movement and renal and urological system development and function	Migration	Migration of kidney cell lines	0.000108	C3, CHL1, F10, RBP3	4
Cardiovascular disorders, cell death and survival, connective tissue disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease	Atypical hemolytic uremic syndrome	Atypical hemolytic uremic syndrome	0.000907	C3, PLG	2
Organismal injuries and abnormalities and renal and urological disease	Failure	Failure of kidney	0.00237	C3, F10, SERPINC1, LCN2	4
Developmental disorder, hereditary disorder, metabolic disease, organismal injuries and abnormalities, and renal and urological disease	Biotinidase deficiency	Biotinidase deficiency	0.00249	BTD	1
Organismal injuries and abnormalities and renal and urological disease	Septic acute kidney injury	Septic acute kidney injury	0.00249	LCN2	1
Organismal injuries and abnormalities and renal and urological disease	Staghorn calculus	Staghorn calculus	0.00249	PLG	1
Cardiovascular disorders, cell death and survival, connective tissue disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease	Susceptibility to atypical hemolytic uremic syndrome type 5	Susceptibility to atypical hemolytic uremic syndrome type 5	0.00249	C3	1
Organismal injuries and abnormalities and renal and urological disease	End stage renal disease	End stage renal disease	0.00318	C3, F10, SERPINC1	3
Cardiovascular diseases, cell death and survival, connective tissue disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease	Atypical hemolytic uremic syndrome	Acute phase atypical hemolytic uremic syndrome	0.00497	C3	1
Cell-to-cell signaling and interaction and renal and urological system development and function	Adhesion	Adhesion of kidney cell lines	0.00664	C3, F10	2
Organismal injuries and abnormalities and renal and urological disease	Acute tubular necrosis	Acute tubular necrosis	0.00745	LCN2	1
Organismal injuries and abnormalities and renal and urological disease	C3 glomerulopathy	C3 glomerulopathy	0.00745	C3	1
Organismal injuries and abnormalities and renal and urological disease	Nephrosis	Nephrosis	0.00861	C3, F10, SERPINC1	3
Immunological disease, inflammatory disease, inflammatory response, organismal injuries and abnormalities, andrenal and urological disease	Membranoproliferative glomerulonephritis	Membranoproliferative glomerulonephritis	0.00992	C3	1