Angiotensin II Promotes White Adipose Tissue Browning and Lipolysis in Mice

Figure 5

Transcriptomics-based screening of differential gene expression profile. (a) The heat map shows the upregulated and downregulated genes in SWATs from C57BL/6 mice infused with saline or Ang II (2.5 mg/kg/d) for 2 weeks. Each column represents an individual replicate, and replicates for each group. Each row represents an individual gene. The color bar represents the -score-transformed relative expression of normalized counts of genes that are upregulated and downregulated. (b) String diagram of differentially expressed genes (DEGs) based on GO functional enrichment analysis. (c) GO pathway analysis of DEGs between control and Ang II groups. (d) KEGG pathway analysis of DEGs between control and Ang II groups.

(a)

(b)

(c)

(d)