Associations among S100A4, Sphingosine-1-Phosphate, and Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease

Figure 1

The level of S100A4 in control cases and COPD patients and the correlation of pulmonary function with serum S100A4 in COPD patients. The level of S100A4 was detected in control subjects and COPD patients. (a, b) The expression of S100A4 was measured in the lungs through western blotting between COPD patients and control subjects. (a) Representative bands were shown. (b) Quantitative analysis of scanning densitometry was tested. (c, d) The level of S100A4 was detected via ELISA. (c) The level of serum S100A4 was compared between COPD patients and control subjects ( for the CTRL group; for the COPD group). (d) The level of serum S100A4 was compared in COPD patients with different grades. (e–h) The association of serum S100A4 and pulmonary function was evaluated through Pearson’s analysis among COPD patients. (e) S100A4 vs. FEV1. (f) S100A4 vs. FVC. (g) S100A4 vs. FEV1/FVC%. (h) S100A4 vs. FEV1% ( for Grade 1-2 patients; for Grade 3 patients; and for Grade 4 patients). All data were represented as (). .

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