Research Article

Associations among S100A4, Sphingosine-1-Phosphate, and Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease

Table 2

Association of serum S100A4 with pulmonary function in COPD patients.

VariablesUnivariate, (95% CI)Multivariable, (95% CI)

FEV1 (%)-0.470 (-2.079, -1.044)<0.001-0.435 (-1.962, -0.939)<0.001
FEV1/FVC (%)-0.252 (-0.810, 0.156)0.004-0.212 (-0.729, 0.090)0.013
FEV1 (L)-0.405 (-0.041, -0.018)<0.001-0.434 (-0.865, -0.046)<0.001
FVC (L)-0.348 (-0.048, -0.017)<0.001-0.405 (-0.041, -0.018)<0.001

Age, gender, and smoking were adjusted.