ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats

Figure 3

NF-κB/NLRP3 signaling was activated by rAdproNGF and NGF-β. The four groups studied are as follows: control cells, cells exposed to OGD/R 24 h + normal saline (NS), cells exposed to rAdproNGF + OGD/R 24 h, and cells exposed to NGF-β + OGD/R 24 h. NLRP3 and NF-κB were detected by immunofluorescence; ; N.S.: no significance (a, b); .

(a)

(b)