Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies

Figure 7

Group-level comparisons of urinary oxidative stress markers. Natural logarithm of concentrations was compared between accelerated () and nonaccelerated () agers (top panels, -test) and across sexes and smoking history (bottom panels, see Table 1 for sample sizes; two-way ANOVA, Bonferroni post hoc test). (a, e) 8-oxo-7,8-deoxyguanosine (8-oxoG); (b, f) 8-oxo-7,8-deoxyguanosine (8-oxoG); (c, g) dityrosine (DTyr); (d, h) 8-oxo-7,8-deoxyguanosine (iPF₂α-VI). Abbreviations: A: accelerated aging; N: nonaccelerated aging; ♀ns: female nonsmoker; ♀es: female ex-smoker; ♂ns: male nonsmoker; ♂es: male ex-smoker.

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