[Retracted] Combined Association of Low-Density Lipoprotein Cholesterol Levels and Systolic Blood Pressure to the Outcome of Intracerebral Hemorrhage: Data from the China Stroke Center Alliance
Table 3
Association between LDL-C and ICH outcomes in different blood pressure levels among all the included patients.
SBP
LDL-C levels
Case (%)
Univariate analysis
Multivariate analysis
Model 1
Model 2
Model 3
Hematoma expansion
<140 mmHg
<70 mg/dL
214 (9.18)
1.18 (0.99, 1.39)
1.17 (0.99, 1.38)
1.14 (0.96, 1.35)
1.16 (0.90, 1.49)
70-100 mg/dL
364 (8.45)
1.07 (0.93, 1.24)
1.07 (0.93, 1.23)
1.07 (0.93, 1.24)
0.98 (0.79, 1.22)
≥100 mg/dL
477 (7.92)
Ref.
Ref.
Ref.
Ref.
140-180 mmHg
<70 mg/dL
563 (8.93)
1.23 (1.11, 1.36)
1.23 (1.11, 1.36)
1.20 (1.08, 1.33)
1.33 (1.14, 1.54)
70-100 mg/dL
996 (7.51)
1.02 (0.94, 1.11)
1.02 (0.94, 1.11)
1.04 (0.96, 1.13)
1.13 (1.00, 1.28)
≥100 mg/dL
1515 (7.36)
Ref.
Ref.
Ref.
Ref.
≥180 mmHg
<70 mg/dL
325(9.97)
1.16 (1.02, 1.32)
1.15 (1.01, 1.31)
1.16 (1.02, 1.33)
1.14 (0.97, 1.35)
70-100 mg/dL
617 (8.35)
0.95 (0.86, 1.06)
0.95 (0.86, 1.06)
0.97 (0.87, 1.07)
0.93 (0.81, 1.06)
≥100 mg/dL
1045 (8.71)
Ref.
Ref.
Ref.
Ref.
for interaction
0.649
0.646
0.608
0.255
In-hospital mortality
<140 mmHg
<70 mg/dL
51 (2.19)
1.38 (0.98, 1.95)
1.32 (0.93, 1.86)
1.34 (0.95, 1.90)
1.13 (0.72, 1.76)
70-100 mg/dL
66 (1.53)
0.96 (0.70, 1.32)
0.94 (0.69, 1.30)
0.96 (0.70, 1.32)
0.98 (0.66, 1.46)
≥100 mg/dL
96 (1.59)
Ref.
Ref.
Ref.
Ref.
140-180 mmHg
<70 mg/dL
128 (2.03)
1.39 (1.13, 1.71)
1.27 (1.03, 1.57)
1.25 (1.01, 1.54)
0.99 (0.76, 1.30)
70-100 mg/dL
203 (1.53)
1.04 (0.87, 1.25)
0.98 (0.82, 1.17)
0.99 (0.82, 1.18)
0.86 (0.69, 1.08)
≥100 mg/dL
302 (1.47)
Ref.
Ref.
Ref.
Ref.
≥180 mmHg
<70 mg/dL
117 (3.59)
1.13 (0.92, 1.40)
1.06 (0.86, 1.32)
1.07 (0.87, 1.33)
0.80 (0.61, 1.04)
70-100 mg/dL
231 (3.13)
0.98 (0.83, 1.16)
0.94 (0.80, 1.11)
0.97 (0.82, 1.14)
0.86 (0.70, 1.06)
≥100 mg/dL
382 (3.19)
Ref.
Ref.
Ref.
Ref.
for interaction
0.667
0.697
0.715
0.647
Data are OR (95% CI) unless otherwise stated. Model 1 adjusted for age and sex. Model 2 adjusted for variables in model 1 plus body mass index (<25.0 or ≥25.0 kg/m2), systolic blood pressure, diastolic blood pressure, smoking status, drinking status, hypertension, diabetes mellitus, previous ICH, medication history (including prior use of antiplatelet, anticoagulant, antihypertensive agent, and stains), and creatinine. Model 3 adjusted for variables in model 2 plus GCS score on admission as a sensitivity analysis.
