[Retracted] Macrophage Rmp Ameliorates Myocardial Infarction by Modulating Macrophage Polarization in Mice

Figure 2

Macrophage Rmp deficiency aggravates cardiac dysfunction after myocardial infarction. (a) Survival curves for macrophage-specific Rmp-knockout (MRKO) and littermate control (LC) mice. . mice per group. (b) Representative images of the hearts from LC and MRKO mice collected 7 days after myocardial infarction (MI). Scale  mm. (c) Representative images of infarct size after Masson’s trichrome staining of the hearts collected 7 days after the induction of MI. (d) Quantification of fibrosis as a percentage of total myocardial tissue area. Values are of per group. Student’s test, . (e) Representative echocardiography (M-mode) and left ventricular function 7 days after the induction of MI. (f) Echocardiographic analysis of LVEF and LVEDV (; Student’s test, ). (g) Immunohistochemical staining of collagen I accumulation at the infarct site 7 days after the induction of MI. Scale  μm. (h) Quantitative analysis of collagen I (; Student’s test, ).

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