The Ethanolic Extract of Lindera aggregata Modulates Gut Microbiota Dysbiosis and Alleviates Ethanol-Induced Acute Liver Inflammation and Oxidative Stress SIRT1/Nrf2/NF-<i>κ</i>B Pathway

<div>Regulation of <i>Lindera aggregata</i> on the diversity of gut microbiota in rats. (a) Sankey diagram shows the abundance and affiliation of microorganisms at different taxonomic levels in the gut of rats under different treatment strategies. (b) Shannon rarefaction curves. (c) Chao1 rarefaction curves. (d) Simpson rarefaction curves. (e) Principle coordinate analysis (PCoA) analysis based on weighted UniFrac distance of gut microbiota of rats in different treatment groups. ANOSIM was used for similarities in PCoA. (f) Nonmetric multidimensional scaling (NMDS) analysis based on weighted UniFrac distance of gut microbiota of rats in different treatment groups. When stress is less than 0.05, the data is considered well representative.</div>

Oxidative Medicine and Cellular Longevity

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Figure 4: The Ethanolic Extract of Lindera aggregata Modulates Gut Microbiota Dysbiosis and Alleviates Ethanol-Induced Acute Liver Inflammation and Oxidative Stress SIRT1/Nrf2/NF-<i>κ</i>B Pathway 

Figure 4 | The Ethanolic Extract of Lindera aggregata Modulates Gut Microbiota Dysbiosis and Alleviates Ethanol-Induced Acute Liver Inflammation and Oxidative Stress SIRT1/Nrf2/NF-κB Pathway 