Research Article

Gandi Capsule Improved Podocyte Lipid Metabolism of Diabetic Nephropathy Mice through SIRT1/AMPK/HNF4A Pathway

Figure 3

Renal histologic changes and lipid accumulation in 18-week-old db/db mice treated with GDC or baicalin. (a) H&E, (b) Oil red O stain, and (c) immunohistochemistry staining for podocin were presented about diabetic nephropathy mice treated by DGC. Scar bar, 100 μm. Valsartan group as a positive control. (d) H&E, (e) Oil red O stain, and (f) immunohistochemistry staining for podocin were presented about diabetic nephropathy mice treated by baicalin. Scar bar, 100 μm. (g–j) Triglyceride and cholesterol levels were analyzed by colorimetric assay of renal tissue. , , and .
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