Glaucocalyxin B Attenuates Ovarian Cancer Cell Growth and Cisplatin Resistance In Vitro via Activating Oxidative Stress

Figure 5

GLB and cisplatin cooperate to increase ROS levels. (a, b) A2780 or A2780/DDP cells were treated with GLB or cisplatin alone or their combination for 2 h; the intracellular ROS levels were monitored by fluorescent probe DCFH-DA.  μm. (c) A2780 or A2780/DDP cells were treated with GLB or cisplatin alone or their combination for 20 h; the formation of 53BP1 foci was analyzed using a fluorescence microscope.  μm. Data from three technical replicates (, ).

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