Oxidative Medicine and Cellular Longevity

Research Article

Explore the Therapeutic Composition and Mechanism of Schisandra chinensis-Acorus tatarinowii Schott on Alzheimer’s Disease by Using an Integrated Approach on Chemical Profile, Network Pharmacology, and UPLC-QTOF/MS-Based Metabolomics Analysis

Table 2

10 drug ingredient information.


Peak	tR (min)	Identification	Formula	Positive ion				Negative ion
				Quasimolecular mass (Da)	Observed mass (Da)	Calculated molecular ion	ppm	Quasimolecular mass (Da)	Observed mass (Da)	Calculated molecular ion	ppm

1	9.86	Longikaurin A	C₂₀H₂₈O₅	[M+Na]⁺	348.1936	348.2903	0	—	—	—	—
2	10.8	Deoxyshikonin	C₁₆H₁₆O₄	[M+H]⁺	273.1119	273.1127	-0.9	—	—	—	—
3	4.06	Angeloylgomisin O	C₂₈H₃₄O₈	[M+H]⁺	499.2316	499.2332	—	[M+HCOO]^-	543.2235	543.223	-0.1
4	8	Schizandrer B	C₂₈H₃₄O₉	[M+NH⁴]⁺	515.2274	532.2547	—	—	—	—	—
5	6.16	Gomisin-A	C₂₃H₂₈O₇	[M+Na]⁺	439.1726	439.1733	—	—	—	—	—
6	9.1	Wuweizisu C	C₂₂H₂₄O₆	[M+H]⁺	385.1646	385.1651	0.1	—	—	—	—
7	5.22	Marmesin	C₁₄H₁₄O₄	[M+NH₄]⁺	264.1218	264.1236	-4.8	—	—	—	—
8	9.66	8-Isopentenyl-kaempferol	C₂₀H₁₈O₆	—	—	—	—	[M-H]^-	353.1043	333.1279	3.4
9	8.47	EUDESMINE	C₂₂H₂₆O₆	[M+H]⁺	387.18	387.1808	-0.5	—	—	—	—
10	0.6	Kaempferol	C₁₅H₁₀O₆	[M+NH₄]⁺	304.0804	304.0821	-3.8	—	—	—	—