Macrophage Infiltration Reduces Neurodegeneration and Improves Stroke Recovery after Delayed Recanalization in Rats

<div>The effects of delayed recanalization on hemorrhage and edema volumes. (a) Representative image of brain edema detected via MRI-DWI scanning before and 1 day after recanalization. (b) MRI-DWI hyperintensity volume measured before and 1 day after recanalization. (c) Brain water content measured via dry/wet method in pMCAO group, rMCAO group, and 1-day recanalization. (d) Hematoma incidence was measured by calculating the occurrence of hematoma detected on MRI images. (e) Representative image of hematoma expanding after recanalization. The hypointense signal outlined on MRI-T2 images indicated acute hematoma. Yellow lines (bottom row) outline the hematoma edge after recanalization, and the white lines (top row, middle two images) outline the hematoma prior to recanalization. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Macrophage Infiltration Reduces Neurodegeneration and Improves Stroke Recovery after Delayed Recanalization in Rats 