Macrophage Infiltration Reduces Neurodegeneration and Improves Stroke Recovery after Delayed Recanalization in Rats

Figure 7

Macrophage depletion reduces neurological recovery. (a) Brain tissue loss visualized by coronal Nissl staining for sham, pMCAO, rMCAO+PBS, and rMCAO+CLP groups. (b) Representative images of neurofilament protein staining in each group. (c) The infarction volume was calculated from Nissl stained sections. (d) Neurological scores acquired in each group. (e) Escape latency in the water maze test. (f) Path length in the water maze test. (g) Beam walking balance score. (h) Probe quadrant duration in the water maze test. (i) Representative examples of water maze tracking. Error bars represent (Q1 to Q3) for (d, g). Error bars represent the for (c, e, f, h). and vs. sham group; ^# and ^## vs. rMCAO group; ^& and ^&& vs. rMCAO+PBS ().

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