AKG Attenuates Cerebral Ischemia-Reperfusion Injury through c-Fos/IL-10/Stat3 Signaling Pathway

Figure 4

AKG inhibited the inflammatory response, oxidative stress, and apoptosis induced by OGD/R in SH-SY5Y cells. (a–c) The levels of proinflammatory cytokines were measured using ELISA (). (d) The levels of SOD were determined using a SOD kit (). (e and f) The levels of superoxide anions as determined by DCFH-DA staining are shown in representative photos and quantitative analysis (). (g and h) Quantification of TUNEL-positive cells in SH-SY5Y cells in the indicated groups () (TUNEL, green; DAPI, blue). and versus the control group and ^# and ^## versus the OGD/R group.

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