Research Article

CTRP7 Is a Biomarker Related to Insulin Resistance and Oxidative Stress: Cross-Sectional and Intervention Studies In Vivo and In Vitro

Figure 7

CTRP7 overexpression facilitates insulin resistance and oxidative stress. Hepa1-6 cells were transfected with pLVX-Puro or pLVX-CTRP7 for 24 h and then exposed BSA or FFAs for another 24 has indicated in the methods. (a) mRNA expression of genes related to glucose metabolism. (b) Effect of CTRP7 overexpression on phosphorylation of insulin signaling molecules. (c) Intracellular ROS is shown with DCFH staining (green). (d) Quantitative analysis of DCFH-DA staining. (e) Intracellular SOD activity. (f) Intracellular GSH levels. (g) Intracellular MDA content. Data are presented as ; or .
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