α-Ketoglutarate Improves Meiotic Maturation of Porcine Oocytes and Promotes the Development of PA Embryos, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway

<div>Effects of α-KG on Caspase3 and Bcl2 of mature oocytes. (a) Representative pictures of Caspase3 immunofluorescence staining in the control group and α-KG-supplemented group. (b) Analysis of the relative fluorescence intensity of Caspase3 in the control group and α-KG-supplemented group. (c) Representative pictures of Caspase3 immunofluorescence staining of blastocysts in each group. (d) Analysis of Bcl2 relative fluorescence intensity of blastocysts in each group. (e) The relative expression of proapoptotic genes (p53, Caspase3, and BAD) mRNA in the control group and the α-KG addition group. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: α-Ketoglutarate Improves Meiotic Maturation of Porcine Oocytes and Promotes the Development of PA Embryos, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway

Figure 5 | α-Ketoglutarate Improves Meiotic Maturation of Porcine Oocytes and Promotes the Development of PA Embryos, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway 