Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21

Figure 4

The miR-21 expression and dual-luciferase reporter analysis (): (a) the qPCR analysis of miR-21 expression in each group; (b) dual-luciferase reporter analysis between miR-21 and PDCD4 (A represents values compared to the NC group, ; B represents values compared to the HR group, ; C represents values compared to the OE-PPARγ group, ; D represents values compared to the sh-PPARγ group, ; E represents values compared to the mimic group, ; F represents values compared to the inhibitor group, ; G represents values compared to the OE-PPARγ+HR group, ; H represents values compared to the sh-PPARγ+HR group, ; I represents values compared to the mimic+HR group, ; J represents values compared to the inhibitor+HR group, ; represents values compared to the NC mimics+m-Pdcd4-3-UTR-wt group, ).

(a)

(b)