Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21

Figure 5

Expression of PPARγ, PDCD4, and cleaved caspase-3 proteins: (a) PPARγ and cleaved caspase-3 protein expressions in PPARγ overregulated and simultaneously miR-21 cotransfection groups; (b) PDCD4 protein expressions in PPARγ overregulated and simultaneously miR-21 cotransfection groups; (c) PPARγ and cleaved caspase-3 protein expressions in PPARγ downregulated and simultaneously miR-21 cotransfection groups; (d) PDCD4 protein expressions in PPARγ downregulated and simultaneously miR-21 cotransfection groups (A represents comparison with NC group, ; B represents comparison with HR group, ; C represents comparison with mimic+HR group, ; D represents comparison with OE-PPARγ+HR group, ; E represents comparison with inhibitor+HR group, ).

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