Potential Therapeutic Effects of Mi-Jian-Chang-Pu Decoction on Neurochemical and Metabolic Changes of Cerebral Ischemia-Reperfusion Injury in Rats

Table 2

Potential biomarkers of cerebral ischemic reperfusion treatment with MJCPD in positive ion mode.

No.		RT (min)	Formula	Name	Adduct	IR vs. SHAM	MJCPDM vs.IR
1	132.1016	1.46	C6H13NO2	L-Isoleucine	M+H	↑^##	↓
2	166.0861	1.69	C9H11NO2	L-(-)-Phenylalanine	M+H	↑^#	↓
3	468.3079	7.32	C22H46NO7P	PC (14 : 0/0 : 0)	M+H	↓^#	↑
4	166.0862	0.82	C9H11NO2	D-Phenylalanine	M+H	↑^#	↓
5	149.0231	10.98	C8H6O4	5-Formylsalicylic acid	M+H2O-H	↑^#	↓
6	510.3549	9.85	C25H52NO7P	1-Heptadecanoyl-sn-glycero-3-phosphocholine	M+H	↑^##	↓
7	496.3391	8.58	C24H50NO7P	PC (16 : 0/0 : 0)	M+H	↑^#	↓
8	132.0766	0.71	C9H9N	3-Methylindole	M+H	↑^##	↓
9	331.284	14.23	C19H38O4	Glycerol 1-hexadecanoate	M+H	↑^##	↓
10	205.0971	1.92	C11H12N2O2	L-Tryptophan	M+H	↓^##	↑
11	182.081	1.43	C9H11NO3	L-Tyrosine	M+H	↑^##	↓
12	112.0503	1.09	C4H5N3O	Cytosine	M+H	↑^#	↑
13	522.3545	9.68	C26H52NO7P	1-Oleoyl-sn-glycero-3-phosphocholine	M+H	↓^###	↑
14	116.0704	0.71	C5H9NO2	DL-Proline	M+H	↓^##	↑
15	329.2474	14.09	C22H32O2	Docosahexaenoic acid	M+H	↑^##	↑
16	524.371	0.83	C26H54NO7P	1-Stearoyl-sn-glycerol-3-phosphocholine	M+H	↑^##	↓
17	132.1015	0.81	C6H13NO2	D-Leucine	M+H	↑^##	↓
18	118.0648	2.16	C5H10O3	DL-a-Hydroxyvaleric acid	M+H	↑^#	↓
19	162.0224	0.68	C5H9NO3S	N-Acetyl cysteine	M-H	↑^#	↓
20	128.0425	0.62	C5H7NO3	Pyroglutamic acid	M+H	↑^#	↓
21	117.0316	18.96	C4H6O4	Acetoacetate	M+H	↓^##	↑

#, ^##, and ^### as compared to the SHAM group; , , and as compared to the IR model group.