Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF-<i>κ</i>B Signaling in Prostate Cancer

<div>CXCL14 knockdown inhibited PC cell progression. (a) The mRNA expressions of CXCL14 and PD-L1 in PC LNCaP and PC-3 cells treated with siRNA against CXCL14 (si-CXCL14) or siRNA negative control (si-NC). (b) The protein expressions of CXCL14 and PD-L1 in PC LNCaP and PC-3 cells treated with siRNA against CXCL14 (si-CXCL14) or siRNA negative control (si-NC). (c) CCK-8 assay for LNCaP and PC-3 cells treated with si-NC or si-CXCL14. (d) Colony formation assay for LNCaP and PC-3 cells treated with si-NC or si-CXCL14. (e) Flow cytometry analysis for LNCaP and PC-3 cells treated with si-NC or si-CXCL14. (f) Wound healing assay for LNCaP and PC-3 cells treated with si-NC or si-CXCL14. (g) Transwell invasion assay for LNCaP and PC-3 cells treated with si-NC or si-CXCL14. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF-<i>κ</i>B Signaling in Prostate Cancer 

Oxidative Medicine and Cellular Longevity

Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF-κB Signaling in Prostate Cancer

Figure 2