Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF-<i>κ</i>B Signaling in Prostate Cancer

<div>Exosomes mediated the role of CXCL14 in M2 macrophage polarization. (a) Transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA) for the morphology and size of exosomes derived from LNCaP cells. Scale bar: 100 <i>μ</i>m. (b) The protein expressions of exosomal markers CD81 and Hsp70 in LNCaP cell lysis or exosomes derived from LNCaP cells. (c) The protein expression of CXCL14 in PMA-pretreated THP-1 cells (M0) treated with PBS (NC) or exosomes derived from LNCaP cells. (d) Immunofluorescence assay for PMA-pretreated THP-1 cells (M0) treated with exosomes (red) derived from LNCaP cells. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF-<i>κ</i>B Signaling in Prostate Cancer 

Oxidative Medicine and Cellular Longevity

Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF-κB Signaling in Prostate Cancer

Figure 4