[Retracted] Lead Exposure Induced Neural Stem Cells Death via Notch Signaling Pathway and Gut-Brain Axis

Figure 3

Suppression of cognitive deficits induced by Pb exposure are prevented by inhibition of Notch signaling. (a) Western blot analysis and shading analysis of Notch1, RBP-J, Hes1, and Hes2 in DG in Hippocampus in the three groups. (b) Western blot analysis and shading analysis of Notch1, RBP-J, Hes1, and Hes2 in olfactory bulb in the three groups. (c) Western blot analysis and shading analysis of Notch1, RBP-J, Hes1, and Hes2 in DG in Control, high-dose Pb exposure, DAPT, and high-dose Pb exposure+DAPT groups. (d) Freeze time during the cue and contextual fear conditioning test in the four groups. (e) Swimming speed, Platform+Edge frequency, and Lantency period during Morris water maze test in the four groups. ,.

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