Research Article
Urocortin I Protects against Myocardial Ischemia/Reperfusion Injury by Sustaining Respiratory Function and Cardiolipin Content via Mitochondrial ATP-Sensitive Potassium Channel Opening
Figure 7
Cardiolipin content after MIRI. (a) Standard chromatogram of cardiolipin: cardiolipin concentration was 500 ng/10 μL, and the injection volume was 10 μL . (b), Chromatogram of myocardial mitochondrial phospholipid sample to be tested: the incoming sample was myocardial mitochondrial phospholipid extraction liquid, and the injection volume was 10 μL.After 40 min ischemia, rat hearts were subjected to MIRI. At the end of reperfusion, cardiolipin content was determined by HPLC. (c) and (a) Cardiolipin content at T1 and T2. ( in each group). . (b) Cardiolipin content at T2 in different group. ( in each group). ##, △△, ◇◇. MIRI: myocardial ischemia-reperfusion injury; HLPC: high performance liquid chromatography; 5-HD: 5-Hydroxydecanoic acid sodium; T1: at the end of balance; T2: at the end of reperfusion; : intragroup comparison with T1; #: compared with N1 the group; △: compared with the IR group; ◇: compared with the U1 group.
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