Clinical Relevance and Tumor Growth Suppression of Mitochondrial ROS Regulators along NADH:Ubiquinone Oxidoreductase Subunit B3 in Thyroid Cancer

Figure 1

mitoROS regulators are associated with clinical outcomes in thyroid cancer. (a) Heatmap depicting consensus clustering solution () for 35 mitoROS regulators in 510 thyroid cancer samples; red represents high expression, and blue represents low expression. (b) Relationship between mitoROS regulator-stratified 3 clusters and clinicopathological variables and in thyroid cancer patients. The unpaired -test was used to analyze statistical assessments. The association between mitoROS levels and clinical characteristic variables was analyzed using the Pearson chi-squared test or Fisher’s exact test. (c) Kaplan–Meier survival analysis of the three groups based on mitoROS regulator-dependent consensus clustering. PFS analysis was statistically evaluated using the log-rank test.

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