Research Article

Effects of Long-Term Vagus Nerve Electrical Stimulation Therapy on Acute Cerebral Infarction and Neurological Function Recovery in Post MCAO Mice

Figure 4

VNS treatment can reduce neuronal damage by regulating the expression of apoptosis-related proteins in the cortex around the infarct. (a) Western blots and quantitative analysis for cleaved-caspase3 and Bcl-2. (b) VNS treatment downregulated the expression of cleaved-caspase3 and upregulated the expression of Bcl-2 compared with the pMCAO+VNI group. Data were presented as , . vs. sham+VNS group and # vs. pMCAO+VNS group.
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