HNF4A Regulates the Proliferation and Tumor Formation of Cervical Cancer Cells through the Wnt/β-Catenin Pathway

Figure 3

HNF4A inhibits tumor formation and tumor growth of cervical cancer cells by inhibiting cell proliferation. (a, b) Immunohistochemical staining of HNF4A and Ki67 in xenograft tumor tissues derived from HeLa-GFP cells, HeLa-HNF4A cells, and SiHa-GFP and SiHa-HNF4A cells, respectively. (c, d) Immunoreactivity scores of HNF4A and Ki67 in xenograft tumor tissues derived from HeLa-GFP cells, HeLa-HNF4A cells, SiHa-GFP, and SiHa-HNF4A cells. Data were statistically analyzed by Student’s -test, and values are shown as . The proliferation was detected using growth curves in HeLa-GFP and HeLa-HNF4A cells (e) and SiHa-GFP and SiHa-HNF4A cells (f). The viability was detected by the MTT assay in HeLa-GFP and HeLa-HNF4A cells (g) and SiHa-GFP and SiHa-HNF4A cells (h). , .

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