HNF4A Regulates the Proliferation and Tumor Formation of Cervical Cancer Cells through the Wnt/β-Catenin Pathway

Figure 4

HNF4A inhibited cell proliferation through inducing cell cycle arrest from the G0/G1 phase to S phase. In the flow cytometry figures, the -axis shows the count of effective cells and the -axis shows the DNA content. Each colored area represents the cells of different phases of the cell cycle: blue area refers to the cells in the G0/G1 phase, green area refers to the cells in the S phase, and pink area refers to the cells in the G2/M phase. The cell cycles of HeLa-GFP (a) and HeLa-HNF4A (b) cells were analyzed using flow cytometry, and a quantitative analysis of the cell cycle is shown (c). The cell cycles of SiHa-GFP (d) and SiHa-HNF4A (e) cells and the quantitative analysis (f) are shown. The data were shown as the of three independent experiments. Data were statistically analyzed by Student’s -test, and values are shown as . .

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