Adropin Improves Radiation-Induced Myocardial Injury via VEGFR2/PI3K/Akt Pathway

<div>Characteristics of Ad<sup>-/-</sup> mice. (a) Schematic diagram of Enho knockout obtained by CRISPR/CAS9. (b) Immunohistochemistry of Ad in myocardial tissue of normal or Ad<sup>-/-</sup> mice. It can be seen that the protein expression of Ad in myocardial tissue of Ad<sup>-/-</sup> mice was lost comparing with that in normal mice. (c) The western blotting was further used to detect the protein expression of Ad in myocardial tissue of normal or Ad<sup>-/-</sup> mice and achieved conclusion consistent with immunohistochemistry. (d) The representative images of echocardiography of normal or Ad<sup>-/-</sup> mice. (e–h) The comparison of LVEF, LVFS, LVEDD, and LVESD in normal or Ad<sup>-/-</sup> mice. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Adropin Improves Radiation-Induced Myocardial Injury via VEGFR2/PI3K/Akt Pathway 