Comparative Impact of Various Exercises on Circulating Irisin in Healthy Subjects: A Systematic Review and Network Meta-Analysis

Table 1

Characteristics of the studies included in the network meta-analysis.

Study (year)	Population	Exercised group: age (years)	Control group: age (years)	Exercised group: BMI	Control group: BMI	Sex; (M/F)	Description of exercise training intervention and control	Blood sample	Blood sampling time
Algul et al.; (2017) [22]	Healthy young men					60 M	: aerobic exercise, acute; : 64-76% MHR (moderate-intensity); : 30 min; : one session	Serum	Before and immediately after exercise
Dundar et al.; (2021) [5]	Healthy adolescent boys	13-16	13-16			34 M	: aerobic exercise, chronic (basketball training); : no mention; : 120 min; : 5 sessions/week; : 8 weeks	Serum	Before and after the eight-week exercise program
Fernandez-del-Valle et al.; (2018) [23]	Healthy young adult	Males:	Females:			14 M/12 F	: resistance exercise, chronic; : 70-80% 1RM (high-intensity); : 55 min; : 3 sessions/week; : 3 weeks	Serum	Before and after the exercise
Hecksteden et al. (2013)^A [2]	Healthy men and women					21 M/62 F	: aerobic exercise, chronic; : 60% heart rate reserve; : 45 min; : 3 sessions/week; : 26 weeks	Serum	Before the training period and at 2 to 7 days after the final training bout
Hecksteden et al. (2013)^B [2]	Healthy men and women					30 M/49 F	: resistance exercise, chronic; : two sets of 15 repetitions with 100% of the 20-repetition maximum (high-intensity); : 3 sessions/week; : 26 weeks	Serum	Before the training period and at 2 to 7 days after the final training bout
Izaddoust and Shabani (2017) [24]	Untrained women					16 F	: resistance exercise, chronic; : 65-75% 1RM; : 65 min; : 3 sessions/week; : 8 weeks	Serum	Before and 24 hours the after last training session
Kabak et al.; (2018) [25]	Professional kick-boxers					30 M	: anaerobic exercise, acute; : HIIT; : four 30-s Wingate anaerobic test; : one session	Plasma	Before and after exercise; (within 1 min)
Miyamoto-Mikami et al.; (2015) [26]	Healthy young women and men					16 M/9 F	: aerobic exercise, chronic; : 60-70% vo2max; : 55 min; : 3 sessions/week; : 8 weeks	Serum	Before and after exercise
Murawska-Cialowicz et al.; (2020) [27]	Healthy men					25 M	: aerobic exercise, chronic; : HIIT; : 60 min; : 2 sessions/week; : 8 weeks	Serum	Before and after the 8-week training
Nicolini et al. (2020) [28]	Healthy young men			No mention	No mention	40 M	: anaerobic running, acute; : high-intensity interval exercise; : 17.5 min; : one session	Serum	Before and 30 min after exercise
Qiu et al. (2018) [29]	Healthy adults					16 M	: aerobic running, acute; : 80% vo2max (high-intensity); : 60 min; : one session	Serum	Before and 10 min after exercise
Rodziewicz et al. (2020) [30]	Master endurance master athletes					22 M	: anaerobic running, acute; : high-intensity; : exercise test until exhaustion; : one session	Plasma	Before and 10 min after exercise
Rostami et al. (2019) [31]	Healthy young untrained women					20 F	: aerobic exercise, chronic; : 65-75%MHR (moderate-intensity); : 65 min; : 3 sessions/week; : 8 weeks	Serum	48 h before and 24 h after the last training session
Scharhag-Rosenberger et al. (2014) [13]	Healthy men and women					29 M/45 F	: resistance exercise, chronic; : 16–20 repetitions at 64%–71% 1RM; : 3 sessions/week; : 24 weeks	Serum	Before and after exercise
Kraemer et al. (2014)^A [12]	Healthy men					7 M	: aerobic exercise, acute; : 60% of VO2max (moderate-intensity); : 90 min; : one session	Plasma	Before and 54 min after exercise
Shabani and Izaddoust (2018)^A [32]	Healthy untrained women					18 F	: aerobic exercise, chronic; : 60–75% MHR; : 65 min; : 3 sessions/week; : 8 weeks	Serum	Before and after exercise
Shabani and Izaddoust (2018)^B [32]	Healthy untrained women					17 F	: resistance exercise, chronic; : 70-75% 1RM; : 65 min; : 3 sessions/week; : 8 weeks	Serum	Before and after exercise
Chireh et al. (2018) [33]	Healthy men	18-28	18-28	No mention	No mention	16 M	: anaerobic exercise, chronic; : 50% Wmax; : 10 min; : 3 sessions/week; : 3 weeks	Plasma	Before and 48 h after exercise

Variables presented as . : kind of exercise; : intensity of exercise; : time of each session; : number of sessions; : duration of exercise; MHR: maximum heart rate; HIIT: high intensity interval training; H: hour.