Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice

<div>IL-22 ameliorates clinical symptoms in DSS-induced colitis mice. The mice used in our study were divided into three groups: control, DSS+PBS and DSS+IL-22. (a) The schematic diagram demonstrates the experimental mouse design. (b) Representative images show the differences in colon length among groups. (c) The Kaplan-Meier survival analysis shows the survival time span. (d) Change in body weight presented as percentages. (e) Disease activity index (DAI) was determined by assessing the change in body weight, bleeding, and stool. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice 

Figure 1 | Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice 