Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice

<div>IL-22 inhibited the expression of proinflammatory cytokines in DSS-induced colitis mice colons. qRT-PCR was performed to determine proinflammatory cytokine mRNA expression levels (TNF-<i>α</i>, IL-6, IL-1<i>β</i>, IFN-<i>γ</i>, IL-18, IL-17A, CXCL1, and CCL2) in colon tissue. (b) ELISA assay was used to detect levels of soluble TNF-<i>α</i>, IL-6, IL-1<i>β</i>, and IL-17 in the medium of the colon tissues. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice 

Figure 2 | Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice 