Research Article

Circ_000829 Plays an Anticancer Role in Renal Cell Carcinoma by Suppressing SRSF1-Mediated Alternative Splicing of SLC39A14

Figure 7

Mechanistic graph summarizing a possible regulatory role of circ_000829 in RCC. Circ_000829 inhibits the alternative splicing of SLC39A14 mRNA by binding to SRSF1, thereby inhibiting the proliferation of RCC cells in vitro and tumorigenesis in vivo.