Electroacupuncture Enhances Neuroplasticity by Regulating the Orexin A-Mediated cAMP/PKA/CREB Signaling Pathway in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice

Figure 4

EA at 10 Hz reduces the 24-hour level of OxA in the CSF of SAMP8 mice. (a) The effect of 10 Hz EA treatment on the 24-hour CSF OxA concentration. (b) Comparison of the mean concentration of OxA in the CSF of SAMP8 and SAMR1 mice during the light and dark periods (compared with the rest period (light period), and ; ns: not significant). (c) The mean concentration of OxA in the CSF of SAMP8 and SAMR1 mice in the light and dark periods was compared (; compared with the control group, ; compared with the 10 Hz EA group, ; ns: not significant).

(a)

(b)

(c)