[Retracted] Identification of a miRSNP Regulatory Axis in Abdominal Aortic Aneurysm by a Network and Pathway-Based Integrative Analysis

Figure 6

The effect of AAA risk genes on the AGE-RAGE signaling pathway in diabetic complications in the KEGG database. (a) Boxes with red outlining indicate proteins or related complexes encoded by AAA risk-related genes, and boxes surrounded by orange indicate that the corresponding coding gene contains a miRSNP in the 3-UTR. (b) Schematic diagram of the miRSNP-miRNA-gene-pathway axis. The yellow ellipse indicates a risk gene, the blue ellipse indicates miRNA, and the red five-pointed star indicates that the miRNA target relationship has been experimentally verified. We marked the SNP of the target gene on line between the miRNA and the risk gene. A red outer circle represents the pathway, green represents the AGE-RAGE signaling pathway in diabetic complications, and blue represents the TGF-beta signaling pathway.

(a)

(b)