Research Article

Identification of Prognostic DNA Methylation Signatures in Lung Adenocarcinoma

Figure 3

The relationship between DNA methylation genes and tumor immune cell infiltration in the TCGA-LUAD data set. (a) Gene coexpression network showing that there was a significant positive correlation between most genes. (b) Correlation analysis between the expression profiles of 20 DNA methylation genes and the infiltration of 22 kinds of immune cells. (c) Gene set enrichment analysis (GSEA) was carried out based on the high and low expression states of the TDG gene. (d) TDG gene expression was significantly higher after EGFR mutation. (e) The expression of the TDG gene in the TMB high evaluation group was significantly higher than that in the TMB low evaluation group. (f) The OS of the MBD2 low expression group was better than that of the high expression group.
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