Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations

Figure 2

The pedigree of two families with novel FLNB variants (c.4846A>G and c.7022T>G). (a) Pedigree of a Chinese LRS family. Males and females are indicated by squares and circles. Affected individual is represented by filled symbols. The proband is represented by arrows. (b) Partial DNA sequence of the mutation site (c.7022T>G) in the FLNB gene. (c) Pedigree of a Chinese VDDR-IA family. Males and females are indicated by squares and circles. Affected individual is represented by filled symbols. The proband is represented by arrows. (d) Partial DNA sequence of the mutation site (c.4846A>G) in the FLNB gene.

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