Activation of the P62-Keap1-NRF2 Pathway Protects against Ferroptosis in Radiation-Induced Lung Injury

Figure 2

Cytotoxicity and effective concentration of Fer-1 on RILI cell. (a, b) Changes in colony formation number of A549 cells in six-well plate under different concentrations of Fer-1. (c) A549 cells clone formation rate (PE) and cell survival fraction (SF) under different concentrations of Fer-1. (d, e) OD values and cell inhibition rate of A549 cells in different concentrations of Fer-1 with CCK-8. (f, g) Changes of colony formation number of RILI cells in six-well plate under different concentrations of Fer-1. (h) RILI cells clone formation rate (PE) and cell survival fraction (SF) under different concentrations of Fer-1. (i, j) OD values and cell inhibition rate of RILI cells in different concentrations of Fer-1 using CCK-8 test (data shown as , one-way ANOVA followed by a Bonferroni correction, NS represented no statistical difference. , , and ).

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