Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-<i>κ</i>B Signaling Pathway

<div>The effect of three species of rhubarb with different concentrations on the release of inflammatory factors in EA.hy926 cells induced by LPS. The content of TNF-<i>α</i> in <i>R. officinale</i> (a), <i>R. palmatum</i> (b), and <i>R. tanguticum</i> (c). The content of IL-1<i>β</i> in <i>R. officinale</i> (d), <i>R. palmatum</i> (e), and <i>R. tanguticum</i> (f). The content of IL-6 in <i>R. officinale</i> (g), <i>R. palmatum</i> (h), and <i>R. tanguticum</i> (i). Statistical significance is labeled as below: compared with the control group, <span class="nowrap"><svg height="9.2729pt" id="M48" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.6359 51.1027 9.2729" width="51.1027pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M448 453H361L394 608H355L322 453H214L248 608H210L176 453H79L70 395H163L134 259H35L24 201H120L82 27H120L158 201H266L229 27H267L305 201H395L404 259H318L348 395H439L448 453ZM310 395L280 259H173L202 395H310Z"></path></g><g transform="matrix(.013,0,0,-0.013,6.24,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 352 264C465 271 600 337 600 480ZM508 481C508 351 402 304 329 304C289 304 265 311 250 317L295 559C302 594 310 606 323 611C335 616 350 619 367 619C455 619 508 573 508 481Z"></path></g><g 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-<i>κ</i>B Signaling Pathway 

Oxidative Medicine and Cellular Longevity

Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-κB Signaling Pathway

Figure 3