Molecular Correlates of Early Onset of Diabetic Cardiomyopathy: Possible Therapeutic Targets

<div>Calcium Rhod-2 optical mapping in isolated perfused hearts in different experimental groups. (a) Optical mapping configuration. (b) Comparison of typical calcium transients averaged over defined regions of interest. (c) Map of calcium transient conduction during 1 Hz stimulation. (d) Map of calcium transient duration at 90% recovery (CTD90) during 1 Hz stimulation. Bar charts display the average value of the calcium transient conduction time (e), amplitude (f), and CTD90 (g) changes of the control, low, and high STZ groups. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Molecular Correlates of Early Onset of Diabetic Cardiomyopathy: Possible Therapeutic Targets 