Research Article

IL-6 Deficiency Attenuates Skeletal Muscle Atrophy by Inhibiting Mitochondrial ROS Production through the Upregulation of PGC-1α in Septic Mice

Table 1

Systemic response to CLP and IL-6 knockout.

WT-ShamIL-6 KO-ShamWT-CLPIL-6 KO-CLP

HR (/min)
RR (/min)
pH#
PaCO2 (mmHg)
PaO2 (mmHg)
HCO3 (mM)
Lactate (mM)#
MAP (mmHg)#

Data are expressed as ; vs. WT-Sham group; # vs. WT-CLP group (ANOVA followed by unpaired Student -test, ). CLP: cecal ligation and puncture; MAP: mean arterial blood pressure.