HSPB8 Overexpression Ameliorates Cognitive Impairment in Diabetic Mice via Inhibiting NLRP3 Inflammation Activation

Figure 1

Upregulation of HSPB8 in the hippocampus of DM mice. (a, b) Representative western blot images and quantitative analyses of HSPB8 in the hippocampus of WT and DM mice ( mice per group). , . (c) mRNA levels of HSPB8 in the hippocampus of WT and DM mice were detected by PCR. , . (d) Representative immunofluorescence staining images of HSPB8 (red) in the hippocampus of WT and DM mice. Nuclei were counterstained with DAPI (blue). . (e) Upregulation of HSPB8 was confirmed by western blotting and (f) immunofluorescent staining when injected virus in the hippocampus ( mice per group).

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