Research Article
[Retracted] DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGFβ1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress
Figure 1
5-AZA-DC intervention influenced the regulatory effects of TGFβ1 on DNMT1 and target genes in neuroglial cells under oxidative stress. (a, b) The protein expressions of TGFβ1 in neuroglial HEB, HM, HM06, and SVGP12 cells after TGFβ1OE or shTGFβ1 transfection were determined by western blot. (c, d) HEB cells were subjected to oxyglucose deprivation/reoxygenic stimulation. The mRNA and protein expressions of DNMT1, TGFβ1, PTEN, and TSC2 in cells after TGFβ1OE (or shTGFβ1) transfection and/or 5-AZA-DC treatment were determined by real-time PCR and western blot. Data are shown as . ns: nonsignificant, .
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