The Combination of Individual Herb of Mi-Jian-Chang-Pu Formula Exerts a Synergistic Effect in the Treatment of Ischemic Stroke in Rats

Table 2

Differential metabolites identified in brain sample between sham and model groups.

No	(min)	Exact mass	Formula	Identification	VIP	Trend	Ion mode
1	0.33	147.0652	C6H10O4	Dimethyl succinate	1.54	↑	+
2	0.72	114.0662	C4H7N3O	Creatinine	1.45	↓	+
3	18.75	501.1776	C26H30O10	Limonexic acid	1.69	↓	—
4	1.98	243.0975	C10H14N2O5	Thymidine	1.32	↓	+
5	0.73	168.0561	C5H5N5O2	8-Hydroxyguanine	1.16	↑	+
6	0.74	152.0567	C5H5N5O	2-Hydroxyadenine	1.31	↓	+
7	9.58	251.1653	C15H24O3	3-Methyl-5-pentyl-2-furanpentanoic acid	1.63	↑	—
8	3.56	177.0870	C6H12N2O4	Alanyl-serine	1.56	↓	+
9	17.74	167.0339	C8H6O4	Terephthalic acid	1.46	↑	+
10	10.40	203.1067	C13H14O2	1-(4-Methoxyphenyl)-4-Methyl-1,4-Pentadien-3-one	1.34	↓	+
11	16.53	380.2220	C24H29NO3	Donepezil	1.14	↓	+
12	0.74	426.0547	C15H17N5O6S2	Cefpodoxime	1.66	↑	—
13	0.65	261.0517	C12H10N2O5	Cinoxacin	1.54	↑	—
14	0.77	629.1512	C30H30O15	4-(4-Hydroxyphenyl)-2-butanone O-[2,6-digalloylglucoside]	1.16	↑	—
15	10.03	299.1615	C15H18N6O	Olomoucine	1.51	↑	+
16	1.51	241.1547	C12H20N2O3	Pirbuterol	1.19	↓	+
17	9.50	249.1860	C16H26O2	3-methyl-alpha-ionyl acetate	1.84	↑	—
18	4.37	112.9856	C2HF3O2	Trifluoroacetic acid	1.62	↑	—