DL-3-N-Butylphthalide Promotes Cartilage Extracellular Matrix Synthesis and Inhibits Osteoarthritis Development by Regulating FoxO3a

<div>Molecular mechanism of NBP on inhibiting OA development. NBP possesses protective effect on human OA chondrocytes from apoptosis by regulating PI3K/AKT/FoxO3a pathway (created with <a href="https://biorender.com/">https://biorender.com/</a>).</div>

Oxidative Medicine and Cellular Longevity

fig9

Figure 9

Figure 9: DL-3-N-Butylphthalide Promotes Cartilage Extracellular Matrix Synthesis and Inhibits Osteoarthritis Development by Regulating FoxO3a 